Document Report Card

ID: ALA1125518

Journal: J Med Chem

Title: Sulfonylureas: a new class of cancer chemotherapeutic agents.

Authors: Mohamadi F, Spees MM, Grindey GB.

Abstract: This study summarizes the antitumor properties of a number of sulofenur thiophene analogs against subcutaneously implanted 6C3HED lymphosarcoma with structural modification of the aryl moiety of the sulfonamide portion of the diarylsulfonylureas. The spectrum of activity of N-(p-chlorophenyl)-N'- [(5-methoxy-2-thienyl)sulfonyl]urea in the HXGC3, VRC5, CX-1, and LX-1 cell lines is also presented.

CiteXplore: 1501228

DOI: 10.1021/jm00094a013