Document Report Card

Basic Information

ID: ALA1130585

Journal: Bioorg Med Chem Lett

Title: New antifungals selected by molecular topology.

Authors: Pastor L, García-Domenech R, Gálvez J, Wolski S, García MD.

Abstract: Molecular topology has been applied to find the new lead antimycotic compounds. Among the selected compounds stands out 3,3'-(4,4'-Biphenylene)bis(2,5-diphenyl-2H-tetrazolium chloride), Benztropine mesylate and Dicyclopentamethylenethiuram disulphide, with minimum inhibitory concentrations between 1.6 and 2 micrograms/mL.

CiteXplore: 9873584

DOI: 10.1016/s0960-894x(98)00460-0