Document Report Card
Basic Information
ID: ALA1130611
Journal: Bioorg Med Chem Lett
Title: Synthesis and antibacterial activity of 2-alkoxy penems.
Authors: Afonso A, Hon F, Fett N, Weinstein J, Ganguly AK, Naples L, Hare RS, Miller GH.
Abstract: The phosphite mediated Oxalimide cyclization reaction was extended to 4-dithiocarbonates of N-oxalyl-2-azetidinones to synthesize 2-alkoxy penems 3. In general, the in vitro antibacterial potency of compounds 3 was weak compared to the highly potent 2-alkylthiopenems 2.
CiteXplore: 9873624