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ID: ALA1130683

Journal: Bioorg Med Chem Lett

Title: Aryl C-glycosides: physiologically stable glycomimetics of sialyl Lewis X.

Authors: Kuribayashi T, Ohkawa N, Satoh S.

Abstract: In the course of the search for physiologically stable, structurally simple, and low molecular weight sLeX mimetics, aryl C-glycosides with carboxylic acid functionality 2 were found to be extremely potent inhibitors against L- and P-selectins with IC50 in the low microM range.

CiteXplore: 9873724

DOI: 10.1016/s0960-894x(98)00607-6