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ID: ALA1130716

Journal: Bioorg Med Chem Lett

Title: The solid phase synthesis of a series of tri-substituted hydantoin ligands for the somatostatin SST5 receptor.

Authors: Sciciński JJ, Barker MD, Murray PJ, Jarvie EM.

Abstract: A series of trisubstituted hydantoins has been prepared by a versatile solid phase route employing primary alcohols, amines and amino acids as the monomeric building blocks. Several compounds showed submicromolar affinity in binding assays at recombinant human somatostatin receptors.

CiteXplore: 9934480

DOI: 10.1016/s0960-894x(98)00647-7