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ID: ALA1130774

Journal: Bioorg Med Chem Lett

Title: Pyrazoles, 1,2,4-triazoles, and tetrazoles as surrogates for cis-amide bonds in boronate ester thrombin inhibitors.

Authors: Duncia JV, Santella JB, Higley CA, VanAtten MK, Weber PC, Alexander RS, Kettner CA, Pruitt JR, Liauw AY, Quan ML, Knabb RM, Wexler RR.

Abstract: Substituted pyrazoles, 1,2,4-triazoles, and tetrazoles are good surrogates for cis-amide bonds in a series of boronate ester thrombin inhibitors.

CiteXplore: 9871540

DOI: 10.1016/s0960-894x(98)00104-8