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Adenosine deaminase inhibitors. Synthesis and biological evaluation of aralkyladenines (ARADS).

Basic Information

ID: ALA1130858

Journal: Bioorg Med Chem Lett

Title: Adenosine deaminase inhibitors. Synthesis and biological evaluation of aralkyladenines (ARADS).

Authors: Curtis MA, Varkhedkar V, Pragnacharyulu PV, Abushanab E.

Abstract: Several 9-aralkyladenines have been prepared and their ADA inhibitory activity was determined. A minimum of two carbon atoms separating the aromatic ring from the adenine-bearing carbon (C3') was found essential for potent activity.

CiteXplore: 9873405

DOI: 10.1016/s0960-894x(98)00291-1

Patent ID: