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ID: ALA1130862
Journal: Bioorg Med Chem Lett
Title: Synthesis and acetylcholinesterase inhibitory activity of (+/-)-14-fluorohuperzine A.
Authors: Zeng F, Jiang H, Tang X, Chen K, Ji R.
Abstract: The synthesis of (+/-)-14-Fluorohuperzine A has been accomplished and the ability of this agent to inhibit acetylcholinesterase has been measured. Taking into account its racemic form, this compound exhibits 62 times less potent activity than natural (-)-huperzine A.
CiteXplore: 9873409