Syntheses of 2-[(3,5-dimethyl-4-methoxypyridyl)alkyl]-benzothiazolidine derivatives as a potential gastric H+/K(+)-ATPase inhibitor.

ID: ALA1130895

Journal: Bioorg Med Chem Lett

Title: Syntheses of 2-[(3,5-dimethyl-4-methoxypyridyl)alkyl]-benzothiazolidine derivatives as a potential gastric H+/K(+)-ATPase inhibitor.

Authors: Yoon SH, Seo S, Lee Y, Hwang S, Kim DY.

Abstract: A series of 2-[(3,5-dimethyl-4-methoxypyridyl)alkyl]benzothiazolidine derivatives were synthesized and tested their inhibitory effects on gastric H+/K(+)-ATPase. Compound 4d exhibited potent in vitro inhibitory activity.

CiteXplore: 9873457

DOI: 10.1016/s0960-894x(98)00334-5

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