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ID: ALA1131516
Journal: Bioorg Med Chem Lett
Title: Sialyl Lewis X-polysaccharide conjugates: targeting inflammatory lesions.
Authors: Sakagami M, Horie K, Nakamoto K, Kawaguchi T, Hamana H.
Abstract: A novel system for active targeting of inflammatory lesions has been established. A SLeX-CMPul conjugate (2) showed accumulation that was 2.5-fold higher in inflammatory lesions in vivo than a SLN-CMPul conjugate (4) and 300-fold higher than monovalent SLeX (6).
CiteXplore: 9873622