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ID: ALA1131559
Journal: Bioorg Med Chem Lett
Title: Novel quinolone derivatives as potent antibacterials.
Authors: Lohray BB, Baskaran S, Rao BS, Mallesham B, Bharath KS, Reddy BY, Venkateswarlu S, Sadhukhan AK, Kumar MS, Sarnaik HM.
Abstract: Several 7-(3R,4R-N,N'-dialkyl diaminopyrrolidinyl)-substituted quinolones were synthesized and evaluated for antibacterial activities. 5-Amino-7-(3R,4R-N,N'-dimethyldiamino-6,8-difluoro-1,4-dihydro-1-c yclopropyl -4-oxoquinoline-3-carboxylic acid was found to have potent antibacterial activity against gram +ve organisms.
CiteXplore: 9871611