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ID: ALA1131660

Journal: Bioorg Med Chem Lett

Title: 4-Aryl-2-anilinopyrimidines as corticotropin-releasing hormone (CRH) antagonists.

Authors: Cocuzza AJ, Hobbs FW, Arnold CR, Chidester DR, Yarem JA, Culp S, Fitzgerald L, Gilligan PJ.

Abstract: A series of 4-aryl-2-(N-ethylanilino)pyrimidines has been synthesized as corticotropin-releasing hormone (CRH) inhibitors. The effect of substitution on each aromatic ring on receptor binding was investigated.

CiteXplore: 10230640

DOI: 10.1016/s0960-894x(99)00132-8