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ID: ALA1131661

Journal: Bioorg Med Chem Lett

Title: Use of the Suzuki reaction for the synthesis of aryl-substituted heterocycles as corticotropin-releasing hormone (CRH) antagonists.

Authors: Cocuzza AJ, Chidester DR, Culp S, Fitzgerald L, Gilligan P.

Abstract: The Suzuki reaction has been used to synthesize a variety of aryl-substituted heterocyclic antagonists of the CRH1 receptor. Examples with several different heterocyclic cores are potent CRH receptor ligands.

CiteXplore: 10230641

DOI: 10.1016/s0960-894x(99)00133-x