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ID: ALA1131682
Journal: Bioorg Med Chem Lett
Title: New photoaffinity analogs of paclitaxel.
Authors: Ojima I, Bounaud PY, Ahern DG.
Abstract: Two new photoreactive paclitaxel analogs bearing [3H2]-3-(4-benzoyl)phenylpropanoyl group as the photophore as well as radiolabeling unit at the 7 and 10 positions, respectively, are developed. These new photoreactive analogs showed excellent preliminary results on the photoaffinity labeling of tubulin and P-glycoprotein.
CiteXplore: 10328311