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ID: ALA1131745

Journal: Bioorg Med Chem Lett

Title: Novel C-ring analogues of 20(S)-camptothecin-part-2: synthesis and in vitro cytotoxicity of 5-C-substituted 20(S)-camptothecin analogues.

Authors: Subrahmanyam D, Venkateswarlu A, Venkateswara Rao K, Sastry TV, Vandana G, Kumar SA.

Abstract: A series of 5-C-substituted 20(S)-camptothecin analogues were synthesised and evaluated their in vitro anti-cancer activity. Several of these analogues have showed excellent activity against human tumor cell lines.

CiteXplore: 10397491

DOI: 10.1016/s0960-894x(99)00268-1