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ID: ALA1131747
Journal: Bioorg Med Chem Lett
Title: Derivation of a possible transition-state for the reaction catalysed by the enzyme estrone Sulfatase (ES).
Authors: Ahmed S, James K.
Abstract: We have determined a possible transition-state for the reaction catalysed by the enzyme Estrone Sulfatase (ES) - as a representation of the active site. Using the derived structure, we have superimposed several steroidal and non-steroidal inhibitors in an attempt to rationalise the inhibitory activity of a number of potent inhibitors.
CiteXplore: 10397493