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ID: ALA1131791

Journal: Bioorg Med Chem Lett

Title: 2,2-Dicyanovinyl as a nonaromatic aryl bioisostere: synthesis, binding experiments and SAR studies of highly selective dopamine D4 receptor ligands.

Authors: Haubmann C, Hübner H, Gmeiner P.

Abstract: The phenylpiperazinylmethyl substituted pyrrolylmethylenemalononitriles of type 3 and 4 were synthesized and evaluated as strong and selective dopamine D4 receptor ligands.

CiteXplore: 10450964

DOI: 10.1016/s0960-894x(99)00302-9