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ID: ALA1131803

Journal: Bioorg Med Chem Lett

Title: Novel benzopyrano[3,4-c]pyrrole derivatives as potent and selective dopamine D3 receptor antagonist.

Authors: Dubuffet T, Newman-Tancredi A, Cussac D, Audinot V, Loutz A, Millan MJ, Lavielle G.

Abstract: A new series of benzopyrano[3,4-c]pyrrole derivatives were synthesized and evaluated for their interaction with dopamine D3 versus D2 receptors. Amongst these compounds, 4x (S 33084) was found to be a potent and selective dopamine D3 receptor antagonist.

CiteXplore: 10450981

DOI: 10.1016/s0960-894x(99)00312-1