Document Report Card
Basic Information
ID: ALA1131809
Journal: Bioorg Med Chem Lett
Title: 1-[(Benzofuran-2-yl)phenylmethyl]-triazoles and -tetrazoles - potent competitive inhibitors of aromatase.
Authors: Vinh TK, Ahmadi M, Delgado PO, Perez SF, Walters HM, Smith HJ, Nicholls PJ, Simons C.
Abstract: The synthesis of a series of novel 1-[(benzofuran-2-yl)phenylmethyl]-triazoles and -tetrazoles is described. The compounds were tested for human placental aromatase inhibition in vitro, using [1beta-3H]-androstenedione as the substrate for the aromatase enzyme, the percentage inhibition and IC50 data is included.
CiteXplore: 10450990