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ID: ALA1131905
Journal: Bioorg Med Chem Lett
Title: Tokaramide A, a new cathepsin B inhibitor from the marine sponge Theonella aff. mirabilis.
Authors: Fusetani N, Fujita M, Nakao Y, Matsunaga S, Van Soest RW.
Abstract: A new cathepsin B inhibitor, tokaramide A (1) has been isolated from the marine sponge Theonella aff. mirabilis. Its structure was determined by spectroscopic and chemical methods. Tokaramide A inhibits cathepsin B with an IC50 value of 29.0 ng/mL.
CiteXplore: 10617079