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ID: ALA1131915

Journal: Bioorg Med Chem Lett

Title: Substituted furans as inhibitors of the PDE4 enzyme.

Authors: Perrier H, Bayly C, Laliberté F, Huang Z, Rasori R, Robichaud A, Girard Y, Macdonald D.

Abstract: The synthesis and in vitro activity of a series of substituted furans as a novel structural class of PDE4 inhibitors is described. Comparison of emetic threshold with known PDE4 inhibitors is presented.

CiteXplore: 10091677

DOI: 10.1016/s0960-894x(98)00742-2