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ID: ALA1131929
Journal: Bioorg Med Chem Lett
Title: New lead compounds for brassinosteroid biosynthesis inhibitors.
Authors: Min YK, Asami T, Fujioka S, Murofushi N, Yamaguchi I, Yoshida S.
Abstract: The first brassinosteroid biosynthesis inhibitor is reported. Among newly synthesized triazole derivatives, 4-(4-chlorophenyl)-2-phenyl-3-(1,2,4-triazoyl)butan-2-ol (6) was found to inhibit the growth of cress seedlings, and this inhibition was recovered by the treatment of brassinolide, suggesting that compound 6 primarily inhibits brassinosteroid biosynthesis.
CiteXplore: 10091696