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ID: ALA1131952

Journal: Bioorg Med Chem Lett

Title: Synthesis of tetrasubstituted bicyclo[3.2.1]octenes as potential inhibitors of influenza virus sialidase.

Authors: Jones PS, Smith PW, Hardy GW, Howes PD, Upton RJ, Bethell RC.

Abstract: Several racemic bicyclo[3.2.1]octene derivatives have been synthesised and evaluated as inhibitors of influenza virus sialidases. The 5-acetamido-bicyclo[3.2.1]octenol 4 showed modest activity against influenza A and B virus sialidases.

CiteXplore: 10098673

DOI: 10.1016/s0960-894x(99)00032-3