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ID: ALA1132033

Journal: Bioorg Med Chem Lett

Title: Stabilization of microtubules by Combretastatin D derivatives.

Authors: Couladouros EA, Li T, Moutsos VI, Pitsinos EN, Soufli IC.

Abstract: The effect of five derivatives of Combretastatin D on tubulin polymerization was investigated. All of them were found to stabilize microtubules to various degrees. The derivatives bearing polar substituents were found to be the most active.

CiteXplore: 10571149

DOI: 10.1016/s0960-894x(99)00503-x