Document Report Card

Basic Information

ID: ALA1132056

Journal: Bioorg Med Chem Lett

Title: First hydroxamate inhibitors for carboxypeptidase A. N-acyl-N-hydroxy-beta-phenylalanines.

Authors: Kim DH, Jin Y.

Abstract: A series of N-acyl-N-hydroxy-beta-Phe were designed, synthesized, and shown to have potent inhibitory activity for carboxypeptidase A (CPA). They are the first examples of CPA inhibitors having a hydroxamate functionality.

CiteXplore: 10201830

DOI: 10.1016/s0960-894x(99)00055-4