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ID: ALA1132511

Journal: Bioorg Med Chem Lett

Title: Stereospecific synthesis of a GS 4104 metabolite: determination of absolute stereochemistry and influenza neuraminidase inhibitory activity.

Authors: Lew W, Escarpe PA, Mendel DB, Sweeny DJ, Kim CU.

Abstract: The total synthesis for the determination of the absolute stereochemistry of a GS 4104 metabolite 3 is described. In addition, the influenza neuraminidase inhibitory activity of 3 and related intermediates are reported.

CiteXplore: 10522696

DOI: 10.1016/s0960-894x(99)00479-5