Document Report Card
Basic Information
ID: ALA1132519
Journal: Bioorg Med Chem Lett
Title: Synthesis and sar of 2- and 3-substituted 7-azaindoles as potential dopamine D4 ligands.
Authors: Curtis NR, Kulagowski JJ, Leeson PD, Ridgill MP, Emms F, Freedman SB, Patel S, Patel S.
Abstract: 7-azaindole compounds bearing a cyclic amine moiety linked by a one or two carbon chain attached at the 2- or 3-position were synthesised and evaluated as potential dopamine D4 ligands. Highest affinity and selectivity for the D4 receptor resided in the 3-aminomethyl-7-azaindole series.
CiteXplore: 10098669