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ID: ALA1132671
Journal: Bioorg Med Chem Lett
Title: The synthesis of a new class of oxytocin antagonists.
Authors: Wiśniewski K, Trojnar J, Riviere P, Haigh R, Yea C, Ashworth D, Melin P, Nilsson A.
Abstract: The synthesis of a new class of oxytocin antagonists, with significantly modified C-terminal part, is described. The chemistry of the Mitsunobu reaction was applied to obtain the key derivatives. In spite of the extensive modifications of previously described compound F792, the peptides retain biological activity as oxytocin antagonists.
CiteXplore: 10522694