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ID: ALA1132725

Journal: Bioorg Med Chem Lett

Title: Evaluation of new L-thiocitrulline derivatives as inhibitors of nitric oxide synthase.

Authors: Ware RW, King SB.

Abstract: New derivatives of L-thiocitrulline were prepared and assayed as inhibitors of the three isoforms of nitric oxide synthase. These compounds demonstrated weak inhibitory activity against the NOS isoforms and these results directly support a recently described model of the L-arginine binding site of NOS.

CiteXplore: 11133090

DOI: 10.1016/s0960-894x(00)00567-9