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ID: ALA1132753

Journal: Bioorg Med Chem Lett

Title: Structure-activity relationship study of asiatic acid derivatives against beta amyloid (A beta)-induced neurotoxicity.

Authors: Jew SS, Yoo CH, Lim DY, Kim H, Mook-Jung I, Jung MW, Choi H, Jung YH, Kim H, Park HG.

Abstract: 8 Semi-synthetic derivatives of asiatic acid were prepared and their protective effect against A beta-induced neurotoxicity was evaluated. Among them, asiatic acid (2), and 4, 16 showed 97, 92 and 87% of protective effect, respectively.

CiteXplore: 10673093

DOI: 10.1016/s0960-894x(99)00658-7