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ID: ALA1132842
Journal: Bioorg Med Chem Lett
Title: Novel antifungals based on 4-substituted imidazole: solid-phase synthesis of substituted aryl sulfonamides towards optimization of in vitro activity.
Authors: Saha AK, Liu L, Marichal P, Odds F.
Abstract: The in vitro activity of novel 4-substituted imidazole antifungals was optimized by solid-phase chemistry and parallel synthesis. Potent yeast-selective as well as broad-spectrum antifungal compounds (32 and 20) were discovered.
CiteXplore: 11133080