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ID: ALA1132843

Journal: Bioorg Med Chem Lett

Title: A convenient procedure for the synthesis of nonsymmetrical bivalent selective serotonin reuptake inhibitors using polymer-supported reagents.

Authors: Tamiz AP, Conti P, Zhang M, Johnson KM, Kozikowski AP.

Abstract: A convenient synthesis of nonsymmetrical bivalent inhibitors of the serotonin transporter is described. The synthesis utilizes polymer-supported reagents that allow for rapid access to novel bivalent ligands without the need for isolation or purification of synthetic intermediates.

CiteXplore: 11133081

DOI: 10.1016/s0960-894x(00)00576-x