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ID: ALA1132869

Journal: Bioorg Med Chem Lett

Title: The first synthesis of clausenamine-A and cytotoxic activities of three biscarbazole analogues against cancer cells.

Authors: Zhang A, Lin G.

Abstract: Clausemine-A (3), isolated from the stem and root bark of Clausena excavata, was synthesized using Suzuki cross-coupling and Oxidative coupling as the key step. Compound 3, and the other two structurally related biscarbazoles 1 and 2, showed potent cytotoxic activities against a variety of human cancer cell lines in vitro.

CiteXplore: 10843207

DOI: 10.1016/s0960-894x(00)00158-x