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ID: ALA1133125

Journal: Bioorg Med Chem Lett

Title: A sigma-1 receptor selective analogue of BD1008. A potential substitute for (+)-opioids in sigma receptor binding assays.

Authors: Maeda DY, Williams W, Bowen WD, Coop A.

Abstract: A simple, achiral monoamine sigma-1 (sigma1) receptor selective ligand (sigma2Ki/sigma1Ki>2000) is described, which could replace the chiral (+)-pentazocine or dextrallorphan as a sigma1 masking agent in sigma2 binding assays.

CiteXplore: 10636233

DOI: 10.1016/s0960-894x(99)00590-9