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ID: ALA1133152
Journal: Bioorg Med Chem Lett
Title: Design and synthesis of mimics of S-adenosyl-L-homocysteine as potential inhibitors of erythromycin methyltransferases.
Authors: Hanessian S, Sgarbi PW.
Abstract: A series of indanotriazine C-ribosides were prepared as SAH mimics, and tested for their ability to inhibit erythromycin resistance methylases Erm AM and Erm C'. A carbocyclic analogue derived from quinic acid was also synthesized and tested.
CiteXplore: 10743942