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ID: ALA1133199
Journal: Bioorg Med Chem Lett
Title: Synthesis and uptake of nitric oxide-releasing drugs by the P2 nucleoside transporter in Trypanosoma equiperdum.
Authors: Soulère L, Hoffmann P, Bringaud F, Périé J.
Abstract: A series of S-nitrosothiols, structurally related to the NO*-donor S-nitroso-N-acetylpenicillamine, and of organic nitrate esters that contain amidine groups which specify a recognition via the trypanosomal purine transporter P2, were synthesized and tested for their ability to inhibit the uptake of [2-(3)H]adenosine on Trypanosoma equiperdum.
CiteXplore: 10890161