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ID: ALA1133204
Journal: Bioorg Med Chem Lett
Title: Synthesis and biological activities of an alpha-methyl and a beta-methyl carbapenem and the corresponding unsubstituted compound.
Authors: Pfaendler HR, Weishaupt R, Meffert H.
Abstract: The carbapenem potassium salts 4, 7 and 8 were prepared. Their rates of beta-lactam hydrolysis and their biological activities, particularly their beta-lactamase inhibiting properties, were examined and explained on the basis of their different substitution and pyramidality.
CiteXplore: 10890171