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ID: ALA1133219

Journal: Bioorg Med Chem Lett

Title: Design and evaluation of dihydroisoquinolines as potent and orally bioavailable human cytomegalovirus inhibitors.

Authors: Chan L, Stefanac T, Turcotte N, Hu Z, Chen Y, Bédard J, May S, Jin H.

Abstract: Following the identification of first pass metabolism issues with our recently described anti-HCMV compounds, the naphthyridines and isoquinolines, we have designed a class of novel metabolically stable and orally bioavailable anti-HCMV agents, the dihydroisoquinolines.

CiteXplore: 10888336

DOI: 10.1016/s0960-894x(00)00265-1