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ID: ALA1133251
Journal: Bioorg Med Chem Lett
Title: Synthesis and biological evaluation of 1-azabicyclo-[3.2.1]octanes: new dopamine transporter inhibitors.
Authors: Tamiz AP, Smith MP, Enyedy I, Flippen-Anderson J, Zhang M, Johnson KM, Kozikowski AP.
Abstract: The synthesis and biological activity of a series of 6-substituted 1-azabicyclo[3.2.1]octanes are described. 1-Azabicyclo[3.2.1]octanes represent a new class of compounds that exhibit monoamine transporter inhibitory activity highly dependent on the overall topology and the absolute stereochemistry of the molecule.
CiteXplore: 10937724