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ID: ALA1133272

Journal: Bioorg Med Chem Lett

Title: A solid-phase synthesis for beta-turn mimetics of sialyl Lewis X.

Authors: Kurokawa K, Kumihara H, Kondo H.

Abstract: A solid-phase synthesis of heterocyclic beta-turn mimetics of sialyl Lewis X, which is a natural carbohydrate ligand of selectins, was established. This synthetic method could be very useful for drug discovery of selectin antagonists using combinatorial chemistry techniques.

CiteXplore: 10969978

DOI: 10.1016/s0960-894x(00)00358-9