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ID: ALA1133281
Journal: Bioorg Med Chem Lett
Title: Synthesis and HIV-1 integrase inhibitory activities of caffeoylglucosides.
Authors: Kim SN, Lee JY, Kim HJ, Shin CG, Park H, Lee YS.
Abstract: Caffeoylglucosides, which have a glucose ring as a central linker, were synthesized from methyl D-glucosides, and their anti-HIV-1 activities were tested. Among them, four dicaffeoylglucosides (IC50 = 29.1+/-35.1 microM), 6a, 6b, 9b and 10b, showed HIV-1 integrase inhibitory activity as potent as L-chicoric acid.
CiteXplore: 10969990