Document Report Card
Basic Information
ID: ALA1133340
Journal: Bioorg Med Chem Lett
Title: Design, synthesis, and structure-activity relationship studies of ATP analogues as DNA gyrase inhibitors.
Authors: Lübbers T, Angehrn P, Gmünder H, Herzig S, Kulhanek J.
Abstract: We report herein the design and synthesis of ATP-analogues, namely 4-amino-pyrazolo[3,4-d]pyrimidines and 4-amino-pyrazolo[1,5-a][1,3,5]triazines, with DNA gyrase inhibitory activity. Among these series, some compounds exhibited promising antibacterial activity.
CiteXplore: 10782694