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ID: ALA1133345
Journal: Bioorg Med Chem Lett
Title: The synthesis and evaluation of 2-substituted-7-(alkylidene)cephalosporin sulfones as beta-lactamase inhibitors.
Authors: Buynak JD, Doppalapudi VR, Rao AS, Nidamarthy SD, Adam G.
Abstract: A series of 2-substituted-7-(alkylidene)cephalosporin sulfones were prepared and evaluated as beta-lactamase inhibitors. Compound 11c showed excellent activity as an inhibitor of the class C beta-lactamase derived from Enterobacter cloacae, strain P99.
CiteXplore: 10853645