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ID: ALA1133352

Journal: Bioorg Med Chem Lett

Title: Synthesis and endothelin receptor binding activity of synthetic analogues of RES-1149-2.

Authors: Kraus GA, Wang X.

Abstract: A direct synthesis of analogues 6 and 7 is described. The key transformations are the addition of dibromomethyl lithium to a ketone and the subsequent mild hydrolysis to a hemiacetal.

CiteXplore: 10853654

DOI: 10.1016/s0960-894x(00)00136-0