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ID: ALA1133408
Journal: Bioorg Med Chem Lett
Title: 5-Arylamino-2-methyl-4,7-dioxobenzothiazoles as inhibitors of cyclin-dependent kinase 4 and cytotoxic agents.
Authors: Ryu CK, Kang HY, Lee SK, Nam KA, Hong CY, Ko WG, Lee BH.
Abstract: 5-Arylamino-2-methyl-4,7-dioxobenzothiazoles were synthesized as inhibitors of cyclin-dependent kinase 4 (CDK4) and cytotoxic agents. Most of the 4,7-dioxobenzothiazoles exhibited selective inhibitory activities for the CDK4 and cytotoxic potential against human cancer cell lines.
CiteXplore: 10743948