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ID: ALA1133496
Journal: Bioorg Med Chem Lett
Title: (1,4-Benzothiazinyloxy)alkylpiperazine derivatives as potential antihypertensive agents.
Authors: Cecchetti V, Schiaffella F, Tabarrini O, Fravolini A.
Abstract: A series of compounds having a piperazine moiety variously linked to the benzothiazine nucleus were synthesized and evaluated for their in vitro alpha-adrenoceptor affinity by radioligand receptor binding assays. Some compounds bearing a oxyalkyl-(2-methoxyphenyl)piperazine side chain were good alpha1-adrenoreceptor ligands.
CiteXplore: 10743949