Document Report Card
Basic Information
ID: ALA1133852
Journal: Bioorg Med Chem Lett
Title: Stereoselective synthesis of 7 alpha- and 7 beta-aminocholestanol as potent fungicidal drugs.
Authors: Fouace S, El kihel L, Dherbomez M, Letourneux Y.
Abstract: Potentially lymphotropic 7 alpha- and 7 beta-aminocholestanol were stereoselectively synthesized. In vitro bioassay studies have shown that these fungicidal lipidic derivatives possess strong antifungal activity against Candida spp resistant strains to amphotericin B, 5-fluorocytosine and azoles.
CiteXplore: 11714599