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ID: ALA1133884

Journal: Bioorg Med Chem Lett

Title: Microwave-assisted [6+4]-cycloaddition of fulvenes and alpha-pyrones to azulene-indoles: facile syntheses of novel antineoplastic agents.

Authors: Hong BC, Jiang YF, Kumar ES.

Abstract: A microwave-enhanced [6+4]-cycloaddition reaction between 6-aminofulvene and pyrones followed by CO(2) extrusion provides azulene-indoles which display interesting antineoplastic activity.

CiteXplore: 11454462

DOI: 10.1016/s0960-894x(01)00349-3