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ID: ALA1133889

Journal: Bioorg Med Chem Lett

Title: Discovery and SAR of org 24598-a selective glycine uptake inhibitor.

Authors: Brown A, Carlyle I, Clark J, Hamilton W, Gibson S, McGarry G, McEachen S, Rae D, Thorn S, Walker G.

Abstract: The discovery of Org 24598, one of the first potent and selective inhibitors of the glycine transporter is discussed. In vitro structure-activity relationships (SARs) data for interaction of a ligand with this system is discussed.

CiteXplore: 11454468

DOI: 10.1016/s0960-894x(01)00355-9