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ID: ALA1133926
Journal: Bioorg Med Chem Lett
Title: Optimization of a screening lead for factor VIIa/TF.
Authors: Young WB, Kolesnikov A, Rai R, Sprengeler PA, Leahy EM, Shrader WD, Sangalang J, Burgess-Henry J, Spencer J, Elrod K, Cregar L.
Abstract: The structure-based design and progression of a screening lead to a 3nM factor VIIa/TF inhibitor with improved selectivity versus related enzymes is described.
CiteXplore: 11527709